Department of Palliative Medicine

Research and publications- Last 3 years

Dr Ashwin Mathur:

1. Serum IGF­1 Levels as Clinical Marker in Assessing the Risk of Lung Cancer International Journal of Biological & Medical Research Res.2018 ;9(3):6441-6443

2. Palliative care awareness in the community: assessed during science of life exhibition at SMS Medical college, Jaipur, Rajasthan, July 2018 Dr Ashwin Mathur, Professor (Medicine), Sawai ManSingh Hospital, Jaipur, Rajasthan,Rajasthan Medical Journal, July 2018

3. Demographic profile of first 2500 patients attending Palliative Care Clinic at a Tertiary care hospital in Rajasthan. Dr Mathur Ashwin, Professor, Dr. Malhotra Hemant, Sr Professor, Department of Medicine, Sawai Mansingh Hospital, Jaipur, Rajasthan, Rajasthan Medical Journal, March 2018

4. Ability of ginger in ameliorating chemotherapy induced side effects in hematological and solid malignancies. Dr Ashwin Mathur (Professor), Department of Medicine, SMS Medical College, Jaipur, Rajasthan. Dr V K Agarwal Global Journal for Research Analysis-Volume 7, Issue 2,Februaryb 2018

5. Vaccination in immune-compromised patients ( review article) Rajasthan University of Health Sciences journal of health sciences, volume 2 number 1, January -march 2017

6. Inoperable carcinoma gallbladder: Comparison of two palliative chemotherapy regimens (gemcitabine-platinum versus CAPEOX) Article in Annals of Oncology 28(suppl_5) · September 2017 Dr Hemant Malhotra; Dr Ashutosh Daga; Dr D Gangopadhyaya; Dr Ashwin Mathur; Dr Bharti Malhotra 

Paper Presentations:

1. Palliative care-Need of the hour-RAJAPICON, AJMER 2018

2. Experiences of newly set up Palliative Care OPD in SMS Hospital, Jaipur  ISSP conference  Jaipur February 2017

3. HbA1C-A marker for Lung Cancer? RAJAPICON,ALWAR 2017

Qualification and Achievements:

1) Completed MBBS from JLN Medical College, Ajmer,1996

2) Completed MD (Internal Medicine) from JLN Medical College, Ajmer,2000

3) 2 months observership  programme in Medical Oncology from IRCH, AIIMS, New Delhi-2009

4) Completed Foundation Course in palliative course conducted by Pallium India, 2009

5) Received  FICP, 2017

6) Six week certificate course in Essentials of Palliative Care 2014

7) One year CTC training organized by Ministry of Health GOI, AIIMS and APHN 2019

8) Palliative Care Always-India; Online course October 2019; Stanford University School of Medicine

Research Activities:

Principal Investigator:

a. A Randomized , Controlled trial to assess the impact of TAMA (Health IT System) on treatment effectiveness in HIV 1 infected subjects initiated on first line anti retroviral therapy

b. A prospective, multi-centre, randomized study to evaluate the safety and efficacy of ZYH1versus Placebo in ART / HIV associated lipodystrophy.

Co Principal Investigator:

1. Epidermal Growth Factor Receptor mutation status in NSCLC patients in Jaipur

2. A Randomized Open Label, Multicenter, Phase 3 study of Epoetin Alfa plus Standard Supportive care versus Supportive care In Anemic Patients with metastatic Breast Cancer receiving Standard chemotherapy

3. A Phase 3 Randomized, open label study of Bosutinib versus Imaninib in subjects with Newly Diagnosed Chronic Phase Philadelphia Chromosome positive Chronic Myelogenous Leukemia

4. A Randomized Double Blind ,Placebo controlled study to evaluate the long term safety and efficacy of Darbopoitin Alfa administerd at 500microgram once every 3 weeks in anemic subjects with advanced stage Non small cell Lung Cancer receiving Multi cycle chemotherapy

5. A Randomized Double blind Phase 3 study comparing Biosimilar  Rituximab (RTXM83) Plus CHOP (R-CHOP) chemotherapy versus a reference Rituximab plus CHOP (R-CHOP) in patients with Diffuse Large B Cell Lymphoma (DLBCL) given as first line chemotherapy

6. Risk Factor estimation for Breast Cancer in India:A case control study

Research:

Elucidation of plasma concentrations of morphine, its metabolites and endorphins in cancer patients and their correlation with pain.

Ongoing research in the Multi Disciplinary Research Unit SMS Medical College, Jaipur

Dr Yogendra Singhal

1. Impact of the various factors on survival of tracheoesophageal fistula patients: A prospective study of 16 patients. Indian Journal of Clinical Anaesthesia, October-December, 2018;5(4):620-624. Dr Shailendra Pareek, dr Lalit Raiger, Dr Yogendra Singhal

2. A prospective, observational audit of failed regional anaesthesia in 4085 caesarean sections at a tertiary care hospital.  Indian Journal of Clinical Anaesthesia, January-March, 2018;5(1):50-55. Dr Seema Partani, dr Yogendra Singhal

3. INTRATHECAL PETHDINE AS A SOLE AGENT IN SPINAL ANAESTHESIA IN LOWER LIMB SURGERIES;A COMPARISON WITH 0.5% BUPIVACAINE HEAVY. J. Hosp. Pharmacy 12(3) July to Sept., 2017.Dr Yogendra Singhal

4.Intraoperative sedation during regional anaesthesia (Caudal epidural anaesthesia) in paediatric patients: Role of intravenous dexemedetomidine. Indian Journal of Clinical Anaesthesia, October-December, 2018;5(4):591-595. Dr Yogendra Singhal, dr Udita Naithani

Dr Gaurav Sharma

1. Dileep Gupta,Vandana Mangal,Gaurav Sharma,Poonam Kalra Efficacy of Magnesium Sulfate as Adjuvant to Ropivacaine 0.4% for Supraclavicular Brachial Plexus Block in Patients undergoing Upper Limb Surgery: A Randomized Controlled Trial JORAPain2017,Vol.3,Issue2;May-Aug 2017:85-89. DOI 10.5005/jp-journals-10046-0075

2. Pranav Jetley,Mamta Khandelwal,Usha Bafna,Gaurav Sharma,Shweta Jain, Debojyoti Dutta Low-dose intravenous alpha-2 agonists as adjuvants to spinal levobupivacaine: A randomized study  Indian Journal of Pain 2017,Vol 31, Issue 1:35-40.  DOI 10.4103/ijpn.ijpn_59_16

3. Dr Gaurav Sharma et al. Comparison of Continuous epidural infusion of Fentanyl-Ropivacaine and Tramadol-Ropivacaine in Management of Postoperative Pain in Obstetric Patient undergoing Lower Section Ceserian Section IOSR Journal of Dental and Medical Sciences Vol.17,Issue3,Ver.1,March 2018.

4. Gaurav Sharma, Samarjit Dey Trigeminal Neuralgia: Radiofrequency Ablation JORA Pain 2018  Vol.4, Issue 1; January-April 2018 :36-38 DOI : 10.5005/jp-journals-10046-0099

5.  Manish Khandelwal, Varun Kumar Saini, Sandeep Kothari, Gaurav Sharma Role of lignocaine nebulization as an adjunct to airway blocks for awake fiber-optic intubation: ...  A comparative study .Anesthesia: Essays and Researches, Year 2018, Volume 12, Issue 3 [p. 735-741] DOI: 10.4103/aer.AER_112_18

6. Dr Deeksha Bindal, Dr Varun Kumar Saini, Dr Gaurav Sharma. Evaluation of Post Operative Analgesia on Adding Dexamethasone with Ropivacaine in Interscalene Brachial Plexus Block for Shoulder Surgery. IOSR JDMS ,Vol.17  Issue9,Sept 2018.DOI: 10.9790/0853-1709074144

7. Saxena AK, Jain P, Dureja GP,Venkitachalam A,Goswami S,Usmani H, Sharma Gaurav et al. Pharmacological Management of Neuropathic Pain in India: A consensus statement from Indian Experts. Indian J Pain 2018;32:132-44

8. Vandana Mangal,Tuhin Mistry,Gaurav Sharma,Md.Kazim et al. Effect of Dexmedetomidine as an adjuvant to ropivacaine in ultrasound guided supraclavicular brachial plexus Block:A prospective,randomized,double blind study.J Anaesthesiol Clin Pharmacol.2018 Jul-Sep;34(3): 357-361 Doi: 10.4103/joacp.JOACP_182_17