Research & Publication
IRD, Jaipur
Research & Publication for Jan-Dec 2018
1. Rajawat GS, Singh AK, Kurian T, Koolwal S. A Rare Differential Diagnosis of Crazy Paving Pattern. Indian J Med Paediatr Oncol 2018;39:415-6.
2. Sharma VK, Jain S, Joshi V, Khippal N. Osteoporosis and correlates in chronic obstructive pulmonary disease. RUHS Journal of health sciences 2018;3:73-77.
3. Jain S, Rathore YS, Joshi V, Khippal N. Clinical, radiological, microbiological profile of pulmonary aspergillosis in treated case of pulmonary tuberculosis. Indian journal of allergy, asthma and immunology 2018;32:74-77.
4. Singh S, Jindal A. A 45-year-old man presenting with chest pain. Lung India 2018;35:171-2.
5. Singh S, Collins BF, Bairwa M, Joshi JM, Talwar D, Singh N, Samaria JK, Mangal DK, Singh V, Raghu G. Hypersensitivity pneumonitis and its correlation with ambient air pollution in urban India. ERJ 2018. DOI: 10.1183/13993003.01563-2018.
6. Mishra MK, Jain S, Sharma A, Jain VK. Pattern of drug resistance in previously treated pulmonary tuberculosis with line probe assay. Annals of international medical and dental research July-August 2018.
7. Rajawat GS, Meena M, Gupta ML, Arora P. Absent unilateral pulmonary artery: a report of two cases. The journal of association of chest physicians 2018;6:72-5.
8. Rajawat GS, Khippal N, Takhar RP. Poland syndrome with associated symbrachydactyly and dextrocardia: a rare case. International journal of research in medical sciences 2018;6:2860-62.
9. Study of copper, zinc and ceruloplasmin albumin ratio in pulmonary tuberculosis. International Journal of Current Research 2017;9:49085-49089.
10. Vitamin D in pulmonary tuberculosis patients in relation to disease severity. International Journal of Current Research 2018;10:71347-71352.
11. Ionic Calcium verses Total Calcium in Relation to Disease Severity and Inflammation in Pulmonary Tuberculosis. International Journal of Medical Science and Current Research 2018;1:23-32.
12. Joshi V, Jain S, Sharma V, Khippal N, Chaturvedi A. Granulomatous hepatitis with military mottling: a rare cause. Journal of the association of physicians of India 2018;66:79-81.
13. Meena LN, Khippal N, Bhandari C, Jenaw RK, Joshi V, Meena S. Anxiety and depression in chronic obstructive pulmonary diseases. International journal of medical science and innovative research 2018;3:13-15.
14. Jain S, Singh AS, Rathore Y. Clinical Puzzle. RMJ Jan 2018.
Awards
Dr Suresh Koolwal
· Presidential oration award, Indian association of bronchology, Coimbatore, Feb 2018
· Fellowship of Royal college of physicians, Edinburgh (FRCP)
· Nominated as National President of Indian Association for Bronchology
Dr Sheetu Singh
· Member of national academy of medical sciences
· Assistant editor, Lung India
· Editor, Lung Rajasthan
Research Work (Clinical trials - Principal Investigator - Dr Narendra Khippal)
A) COPD - Principal investigator - Dr Narendra Khippal
1. A Randomized, 26-Week, Placebo-Controlled Efficacy and Safety Study with a 2week Long-term Safety Extension of High and Medium-Dose Inhaled Mometasone Furoate/Formoterol Fixed-Dose Combination Formulation Compared with Formoterol and High-Dose Inhaled Mometasone Furoate Monotherapy in Subjects with Moderate to Severe COPD.
2. A randomized, double-blind, double dummy, multicentre, Parallel - group study comparing the efficacy and safety of the test HFA formulation of lpratropium bromide with the reference HFA formulation of lpratropium bromide in patients with mild or moderate chronic obstructive pulmonary disease (C0PD).
3. An open label comparative multicentric study to assess the efficacy and safety of fixed-dose combination of Formoterol fumarate & Mometasone furoate Dry Powder Inhaler (DPI) and fixed dose combination formoterol fumarate & Budesonide Dry Powder Inhaler {DPI) for the treatment of bronchial asthma and/or chronic obstructive pulmonary disease (COPD).
4. A randomised, double-blind, active-controlled parallel group study to evaluate the effect of 52 weeks of once daily treatment of orally inhaled tiotropium + olodaterol fixed dose combination compared with tiotropium on Chronic Obstructive Pulmonary Disease (COPD) exacerbation in patients with severe to very severe COPD.[DYNAGITO]
B) BRONCHIAL ASTHMA- Principal investigator -Dr Narendra Khippal
5. An open label, comparative, multicentric study to assess the efficacy and safety of Zileuton extended-release tablets in comparison with Montelukast sodium tablets in patients suffering from bronchial asthma.
6. A phase II, 12 week randomized, double-blind, triple dummy, parallel group, placebo-controlled, dose range finding study to evaluate the safety, tolerability and efficacy of revamilast in subjects with chronic persistent Asthma.
7. A prospective, open label, non-comparative, observational, 24 weeks multicenter study of Fluticasone/Formoterol (Maxiflo®) FDC rotacaps (100/6 mcg and 250/6 mcg) when taken through Revolizer® in patients with persistent asthma.
C) ALLERGIC RHINITIS - Principal investigator - Dr Narendra Khippal
8. A randomized, open label, comparative, multicentric study to assess the efficacy and safety of Acrivastine capsules in comparison with Chlorpheniramine maleate tablets in patients suffering from allergic rhinitis.
D) DEEP VEIN THROMBOSIS - Principal investigator - Dr Narendra Khippal
9. International, multi-centre, randomized, double blind study to compare the overall mortality in acutely ill medical patients treated with enoxaparin versus placebo in addition to Graduated Elastic Stockings.
E) LUNG CANCER - Principal investigator - Dr Narendra Khippal
10. A Randomized, double-blind, placebo controlled Phase 2 trial of Bavituximab plus Docetaxel in patients with previously treated locally Advanced or Metastatic Non Squamous Non-Small-Cell Lung Cancer.
11. A Randomized, open label, phase 2 trial of Paclitaxel/Carboplatin with or without Bavituzimab in patients with previously untreated locally Advanced or Metastatic Non-Squamous Non-Small-Cell Lung Cancer.
12. Phase 3 Study of Pemetrexed, Cisplatin, and Radiotherapy Followed by Consolidation Pemetrexed versus Etoposide, Cisplatin, and Radiotherapy Followed by Consolidation Cytotoxic Chemotherapy of Choice in Patients with Unresectable, Locally Advanced, Stage III Non-Small Cell Lung Cancer Other than Predominantly Squamous Cell Histology.
13. A phase III, multicenter, randomized, double-blind, unbalanced (3:1) active control study to assess the safety and describe the efficacy of netupitant and palonosetron for the prevention of chemotherapy-induced nausea and vomiting in repeated chemotherapy cycles.
F) Community acquired pneumonia -Principal investigator - Dr Narendra Khippal
14. A Phase III, Multicentre, Randomized, Double-Blind, Comparative Study to Evaluate the Efficacy and Safety of Intravenous CeftarolineFosamil Versus Intravenous Ceftriaxone in the Treatment of Adult Hospitalised Patients With CommunityAcquired Bacterial Pneumonia in Asia.
15. A Randomized, Double-blind, Double-dummy, Active-controlled, Multi-centre Trial to Compare the Efficacy and Safety of CSE-1034 (Ceftriaxone+ Sulbactam+ EOTA) with Meropenem in Infections Caused by -Lactamase (ESBL and MBL) producing Gram Negative Bacteria.
16. A Randomized, Multicentre, Double-blind, Double-dummy, Parallel-group Comparative Study to Determine the Efficacy, Safety And Tolerability of Ceftazidime-Avibactam (CAZ-AVI) Versus Meropenem in the Treatment of Nosocomial Pneumonia (NP) Including Ventilator-Associated Pneumonia (VAP) in Hospitalised Adults.
G) HIV - Principal investigator - Dr Narendra Khippal
17. A prospective, multi-centre, double-blind, randomized, study to evaluate the safety and efficacy of Saroglitazar 4mg versus Placebo in the treatment of HIV associated lipodystrophy.
IRD, Jaipur
LIST OF PUBLICATIONS FROM 2014 TO 2017
Dr RK Jenaw
1. Singh S, Jenaw RK, Jindal A, Bhandari C. Hodgkin’s lymphoma presenting as sternal lytic lesion. Lung India 2015;32:410-2.
Dr Shashi Agnihotri
1. Agnihotri S.: Usefulness of Pleural Fluid CRP Level in Differential Diagnosis of Exudative Pleural Effusion-A Pilot Study. International Journal of Clinical Biochemistry Research (IJCBR) Vol.2 Issue.2.
2. Agnihotri S.: Study of Factors influencing response and outcome of Cat-IV Regimen in MDRTB Patients. Indian Jurnal of Tuberculosis IJTB_2016_42.
3. Manju M.D., Singh A.K., Agnihotri S. Role of sputum induction and bronchoscopy in undiagnosed pulmonary tunerculosis. International J Current Medical and Applied Sciences. 2016; 10(3),161-165
4. M. J. Qureshi, N. K. Jain, A. Singh, S. P. Agnihotri, N. Joshi Is catII regimen effective in inh resistant TB? Lung India 2015;32:33.
5. Yadav AK, Mehrotra AK, Agnihotri SP, Swami S. Study of factors influencing response and outcome of Cat IV regimen in MDRTB patients. Ind J Tubercul 2016;63:255-61.
Dr S Koolwal
1. Sehajpal R, Koolwal A, Koolwal S. Assessment of inhalation technique of bronchial asthma and chronic obstructive pulmonary disease patients attending tertiary care hospital in Jaipur, Rajasthan. Indian J Allergy Asthma Immunology, 2014;28:78-82
2. Koolwal A, Kapoor H, Sehajpal R, Koolwal S. Diet and asthma: An observational study. Indian J Allergy Asthma Immunol 2014;28:93-7
3. Mishra S, Vardey S.K., Taparia P., Koolwal S.;Role of Prealbumin and Transferrin in Assessment ofMalnutrition Risk in Pulmonary Tuberculosis Patients. PARIPEX - INDIAN JOURNAL OF RESEARCH, Volume : 5 | Issue : 7 | July 2016.
4. Taparia.P, Yadav. D, Koolwal S., Mishra S., study of lipid profile in pulmonary tuberculosis patients and relapse cases in relation with disease severity: A pilot study-International journal of Sciences and Applied Research ,2 (1),2015,41-50
5. Taparia P, Meena B P, R Faridh, Koolwal S. Calcium Metabolic Profile in Various Categories of Pulmonary Tuberculosis Patients International Journal of Scientific Research, Vol : 4, Issue : 12 December 2015.
Dr Nalin Joshi
1. Joshi N. Evaluation of Thyroid Dysfunction in (COPD), Biomedical Research 2014:24(1):110-113.
2. Joshi N. Biphasic Pulmonary Annual Bcastoma : an unusual Presentations, Lung India Jan 2014.
3. Joshi N. Systemic Scelrosis, Sine Scleroderma : An rare EMTY, Indian Journal of Chest Diseases & Allied sci.
Dr Chand Bhandari
1. Singh S, Jenaw RK, Jindal A, Bhandari C. Hodgkin’s lymphoma presenting as sternal lytic lesion. Lung India 2015;32:410-2.
2. Sirowa M, Meena RC, Soothwal P, Bhandari C, Gupta PR, Bhangoo HS. Role of medical thoracoscopy in undiagnosed exudative pleural effusion. Ind J Basic Applied Medical Research 2017;7:282-87.
3. Khatri R, Meena RC, Gupta PR, Meena S, Bhandari C, Bhangoo HS. Place of active case findingacctivity in detection of relapses in treated patients of DOTS Cat 1 patients. Ind J Basic Applied Medical Research 2017;7:149-55.
Dr Aashish Kumar Singh
1. Singh A.K, Jain V.K, Mishra M. Clinical profile of Bronchial Asthma patients reporting at Respiratory Medicine OPD of teaching hospital. Indian J Allergy Asthma Immunol. Jan-Jun 2015;29:3-6.
2. Singh A.K., Qureshi M.J. Partial Bronchial Tear: An unusual cause of haemoptysis. International J Medicine and Allied Health Sciences 2015;6:615-616.
3. Mishra M., Jain V.K., Singh A K. Hair: An unusual foreign body in airways presenting with haemoptysis in an adult patient. Ind J Chest Dis Allied Sci 2014; 56:45-47.
4. Jain S., Singh A K, Joshi V. Complex aspergilloma presenting as chronic dry cough: An unusual finding. Indian J Allergy Asthma Immunol 2016;30:32-34.
5. Gupta S., Jain V.K., Singh A.K., Mishra M., Ojha T.,Sino-Nasal Status in Patients with Chronic Obstructive Pulmonary Disease. Indian J Chest Dis Allied Sci. 2016;58:99-102.
6. Manju M.D., Singh A.K., Agnihotri S. Role of sputum induction and bronchoscopy in undiagnosed pulmonary tunerculosis. International J Current Medical and Applied Sciences. 2016; 10(3),161-165
7. Jain S., Jain D., Singh A.K., Jain V.K.. An Unusual Presentation in Urinothorax. India J Chest Dis Allied Sci 2016;58:181-183.
8. Jain S., Singh A. K., Joshi V. Complex aspergilloma presenting as chronic dry cough: An unusual finding. Indian J Allergy Asthma Immunol 2016;30:32-4.
9. Rajawat G.S., Singh A.K., Batra S., Gupta M.L., Yadav G.S., Koolwal S. Churg-Strauss syndrome: A rare cause of pleural effusion. Indian J Allergy Asthma Immunol 2016;30:105-8.
Dr Shubhra Jain
1. Gupta P.R., Jain Shubhra. Kewlani J.P. A Comparative Study of itraconazole in treated various dose schedules in the treatment of pulmonary aspergilloma in treated patients of pulmonary tuberculosis Lung India. Vol 32. Issue4. July-Aug 2015.
2. Jain S., Singh A K, Joshi V. Complex aspergilloma presenting as chronic dry cough: An unusual finding. Indian J Allergy Asthma Immunol 2016;30:32-34.
3. Jain S.,Jain D. Singh A.K. “An unuasual presentation in urinothorax. Indian J Chest Dis Allied Sci;58:181-183
Dr Mohammed Javed Qureshi
1. M. J. Qureshi, N. K. Jain, A. Singh, S. P. Agnihotri, N. Joshi Is catII regimen effective in inh resistant TB? Lung India 2015;32:33.
2. Singh A.K., Qureshi M.J. Partial Bronchial Tear: An unusual cause of haemoptysis. International J Medicine and Allied Health Sciences 2015;6:615-616.
Dr Sheetu Singh
1. Singh V, Meena H, Bairwa R, Singh S, Sharma BB, Singh A. Clinico-radiological profile and risk factors in patients with anthracosis. Lung India 2015;32:102-6.
2. Singh S, Jenaw RK, Jindal A, Bhandari C. Hodgkin’s lymphoma presenting as sternal lytic lesion. Lung India 2015;32:410-2.
3. Singh S, Sharma BB, Sharma SK, Sabir M, Singh V. Prevalence and severity of asthma among Indian school children aged between 6 and 14 years: associations with parental smoking and traffic pollution. J Asthma 2015;30:1-7.
4. Singh S, Singh N, Singh V. Transmediastinal herniation of bulla: Semilunar sign. Lung India 2015;32:611-13.
5. Singh N, Singh S, Jain NK, Singh V. Respiratory disease terminology: Discordance between pulmonologists and patients. Lung India 2017;34:9-12.
6. Singh S, Singh N. Current trends of management of respiratory diseases by pulmonologists: Results of National Conference of Pulmonary Disease - 2015 survey. Lung India 2017;34:13-18.
7. Singh V, Singh N, Singh S, Sharma BB. Interstitial Pneumonitis after Cadmium Exposure: Is it Reversible? Ann Clin Case Reports 2016;1:1119
8. Singh S, Sharma BB, Salvi S, et al. Allergic Rhinitis, Rhinoconjunctivitis, and Eczema: Prevalence and Associated Factors in Children. Clin Respir J 2016 Sept 24.
9. Singh N, Singh S, Sharma BB, Singh V. Swine flu fibrosis: Regressive or progressive? Lung India 2016;33:219-21.
10. Singh S, Singh V. Is bronchoalveolar lavage a game changer in the diagnosis of interstitial lung disease? Lung India 2016;33:333-34.
11. Singh S, Singh N, Jindal A. Dry cough in a middle aged man. Lung India 2016;33:657-60.
12. Singh S, Collins BF, Sharma BB et al. Interstitial Lung Disease (ILD) in India: Results of a Prospective Registry. Am J Resp Crit Care Med ;195:801-13. 2017
13. Singh S, Collins BF, Singh V, Raghu G. "Reply: "The ILD-India Registry: Ignoratio Elenchi" and "The ILD-India Registry: Look Before You Leap". Am J Resp Crit Care Med ;195:837-39. 2017
Dr Gulab Singh Yadav
1. Yadav G.S. Knowledge and awareness of the Tuberculosis in Tuberculosis patients at a tertiary care center in North West Rajasthan India (National Journal of Community Medicine/Volume1/Issue 4/April 2016).
2. Yadav G. S. Health seeking behaviour and social stigma for Tuberculosis in Tuberculosis Patients at a tertiary care center in North West India. (International Journal of Medical Science and Public Health/Volume 5/Issue 09/2016.
Dr Govind Singh Rajawat
1. Rajawat G.S., Singh A.K., Batra S, Gupta ML, Yadav GS, Koolwal S. Pleural effusion in Churg-Strauss syndrome. Ind J Allergy asthma immunol 2016;30:105-8.
2. Rajawat G.S., Batra S., Thakar R., Bhandari C, Rathi L., Gupta M.L.Diagnostic yield and safety of closed needle plural biopsy in exudative pleural effusion. [Avicenna Journal of Medicine] Accepted in process of print.